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    <dc:description xml:lang="en">Prickle1 gene floxed mice.  Exon 6 was flanked by loxP sites.</dc:description>
    <ns1:colonyMaintenance xml:lang="en">Homozygote x Homozygote [or Crossing to C57BL/6JJcl]</ns1:colonyMaintenance>
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    <ns1:donorDNA>phage P1 loxP sites, yeast FRT (flipase recombination target) site, mouse Prickle1 genomic DNA</ns1:donorDNA>
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    <ns4:application>Cre/loxP system</ns4:application>
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    <ns1:strainDevelopment xml:lang="ja">大阪大学大学院生命機能研究科・橋本昌和先生、峯岸かつら先生、濱田博司先生ら（2010）。(129 x C57BL/6)F1由来G4 ES細胞を用いて作出。PGK-neoカセットはCAG-FLPeマウス（B6/129背景）との交配により除去。C57BL/6と129の混合背景。</ns1:strainDevelopment>
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    <ns1:ESCellLine>G4 [(129S6/SvEvTac x C57BL/6NCr)F1]</ns1:ESCellLine>
    <dc:description xml:lang="ja">Prickle1遺伝子のfloxedマウス。Prickle1遺伝子のエクソン6の5’側と3’側にloxP配列が挿入されている。</dc:description>
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    <rdfs:label xml:lang="en">B6.Cg-Prickle1&lt;tm1.1Hmd&gt;</rdfs:label>
    <rdfs:label>B6.Cg-Prickle1&lt;tm1.1Hmd&gt;</rdfs:label>
    <skos:altLabel xml:lang="ja">Prickle1 flox, B6-Prickle1 floxed</skos:altLabel>
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    <ns1:expectedDelivery xml:lang="en">D (more than 6 months)</ns1:expectedDelivery>
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    <ns4:application>FLP/frt system</ns4:application>
    <ns4:termsAndConditions xml:lang="en">In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Dev. Cell., 40(5):439-452.e4(2017).</ns4:termsAndConditions>
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    <ns6:brs_depositor xml:lang="ja">濱田　博司</ns6:brs_depositor>
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    <ns5:organism rdf:parseType="Resource">
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    <ns4:termsAndConditions xml:lang="ja">条件を付加する。&lt;br&gt;研究成果の公表にあたって譲渡者の指定する文献を引用する。Dev. Cell., 40(5):439-452.e4(2017).</ns4:termsAndConditions>
    <ns1:expectedDelivery xml:lang="ja">D（6か月以上）</ns1:expectedDelivery>
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    <ns6:brs_depositor xml:lang="en">Hiroshi HAMADA</ns6:brs_depositor>
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    <ns6:brs_strainTypeLink rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/straintype_14"/>
    <ns4:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;</ns4:addinfo>
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    <ns1:strainDevelopment xml:lang="en">Developed by Masakazu Hashimoto, Katsura Minegishi and Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University in 2010.  G4 ES cells derived from (129 x C57BL/6)F1 were used to generate the mutant mice.  A frt flanked PGK-neo cassette was removed by crossing with CAG-FLPe mice (B6/129 background).  C57BL/6 and 129 mixed background.</ns1:strainDevelopment>
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